Body temperature = 37.2-39.5oC
Heart rate = 230-380/min
Respiratory rate = 42-104/min
Tidal volume = 2.3-5.3 ml/kg
Large cecum can act as reservoir for anesthetics. Depending on drug solubility, the cecum can alter the pharmacologic effect.
Induction of anesthesia using volatile anesthetics (e.g., halothane and isoflurane) should be done with caution due to initial breath holding when animals are first exposed to irritating gas vapors.
Body temperature = 37-38oC
Heart rate = 250-500/min
Respiratory rate = 35-135/min
Tidal volume = 0.6-1.4 ml
Syrian or golden hamster is very resistant to morphine - no sedation or hypnotic effects.
Syrian or golden hamster has an increased tolerance to pentobarbital.
Atropine 0.1 mg/kg IP IM SC
Ketamine, C-III (Ketaset®, Vetalar®) 22-44 mg/kg IM
Body temperature = 35.9-37.5oC
Heart rate = 250-450/min
Respiratory rate = 70-115/min
Tidal volume = 0.6-2.0 ml
Male rats and animals receiving low calorie diets require higher doses of barbiturates.
Avertin has been reported to cause ileus in rats.
The therapeutic dose for carbon dioxide is close to the lethal dose; very short acting. Concurrent administration of 10-50% O2 is recommended.
Body temperature = 36.5-38.0oC
Heart rate = 325-780/min
Respiratory rate = 94-163/min
Tidal volume = 0.09-0.23 ml
The use of chloroform as an anesthetic agent is discouraged. Chloroform can cause renal tubular calcification and/or necrosis, particularly in male mice; DBA/2 strain most susceptible.
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SUTURE 1 10.5 - Table 4: Recommended Instrument DisinfectantsAlways follow manufacturer's instructions. 10.4 - Table 3: Recommended Instrument SterilantsAlways follow manufacturer's instructions. |