Chapter 11 - Anesthesia and Analgesia for Laboratory Animals

Policy on Analgesic Use

  • Analgesics must be provided to all animals following survival surgery unless scientific justification for withholding post-operative analgesics is provided by the investigator and approved by the IACUC, or if a veterinarian examines the animal and determines that analgesic administration is no longer necessary.
Submitted by Linda on May 6, 2008 - 1:38pm.

10.6 - Table 5: Suture Selection

SUTURE 1

Submitted by Linda on May 5, 2008 - 12:43pm.

10.5 - Table 4: Recommended Instrument Disinfectants

Always follow manufacturer's instructions.

Submitted by Linda on May 5, 2008 - 12:38pm.

10.4 - Table 3: Recommended Instrument Sterilants

Always follow manufacturer's instructions.

Submitted by Linda on May 5, 2008 - 12:32pm.

10.3 - Table 2: Skin Disinfectants

NAME
Submitted by Linda on May 5, 2008 - 12:23pm.

10.2 - Table 1: Recommended Hard Surface Disinfectants

(e.g., table tops, equipment) Always follow manufacturer’s instructions. 

Submitted by Linda on May 5, 2008 - 11:27am.

10.1 - Procedures and Definitions

Procedures

Pre-Operative

  1. Surgery should be conducted in a disinfected (Table 1), uncluttered area that promotes asepsis during surgery.
  2. Prepare the animal by removing hair from the surgical site.
Submitted by Linda on May 5, 2008 - 11:22am.

Chapter 10 - NIH Intramural Research Program Guidelines for Survival Rodent Surgery

Scope

These guidelines apply to all surgical procedures performed on rodents at the NIH in which the animals are expected to recover from anesthesia.

General

Survival surgery on rodents should be performed using sterile instruments, surgical gloves, masks and aseptic procedures, to reduce microbial contamination of exposed tissues to the lowest practical level. Minor surgical procedures such as wound suturing and peripheral vessel cannulation should be performed in accordance with standard veterinary practices.

Submitted by Linda on May 5, 2008 - 11:13am.

Chapter 9 - Surgery

Surgery and Post-Surgical Care

Individuals performing survival surgical procedures must be knowledgeable of aseptic surgical techniques and have adequate training and skills to conduct the procedure to be performed without causing undue post-surgical distress to the animal. Aseptic techniques must be used for all survival surgical procedures. Aseptic technique is used to reduce contamination of the surgical site to the lowest practical level.

Submitted by Linda on May 5, 2008 - 11:05am.

Chapter 8 - Standards of Animal Husbandry

Laboratory animal husbandry covers three areas: (1) Facilities and operating procedures in facilities, including temperature and humidity, lighting, cage construction and maintenance, cage size, and waste disposal; (2) Animal health and husbandry, including feeding, water, sanitation, staffing, classification and separation, and veterinary care; (3) Transportation, including construction, size, and ventilation of transportation cage, identification of animals, and care in transit.

Submitted by Linda on May 2, 2008 - 2:01pm.
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